| Northern Illinois Huskies vs. Iowa Hawkeyes | Northern Illinois Huskies vs. Iowa Hawkeyes | Soldier Field Stadium | Soldier Field Stadium
Chicago, IL | 09/01/2012 3:30 AM | Sep 01, 2012 TBA | View Tickets |
| Iowa Hawkeyes vs. Iowa State Cyclones | Iowa Hawkeyes vs. Iowa State Cyclones | Kinnick Stadium | Kinnick Stadium
Iowa City, IA | 09/08/2012 3:30 AM | Sep 08, 2012 TBA | View Tickets |
| Iowa Hawkeyes vs. Northern Iowa Panthers | Iowa Hawkeyes vs. Northern Iowa Panthers | Kinnick Stadium | Kinnick Stadium
Iowa City, IA | 09/15/2012 3:30 AM | Sep 15, 2012 TBA | View Tickets |
| Iowa Hawkeyes vs. Central Michigan Chippewas | Iowa Hawkeyes vs. Central Michigan Chippewas | Kinnick Stadium | Kinnick Stadium
Iowa City, IA | 09/22/2012 3:30 AM | Sep 22, 2012 TBA | View Tickets |
| Iowa Hawkeyes vs. Minnesota Golden Gophers | Iowa Hawkeyes vs. Minnesota Golden Gophers | Kinnick Stadium | Kinnick Stadium
Iowa City, IA | 09/29/2012 3:30 AM | Sep 29, 2012 TBA | View Tickets |
| Michigan State Spartans vs. Iowa Hawkeyes | Michigan State Spartans vs. Iowa Hawkeyes | Spartan Stadium - MI | Spartan Stadium - MI
East Lansing, MI | 10/13/2012 12:00 PM | Oct 13, 2012 Sat, 12:00 PM | View Tickets |
| Iowa Hawkeyes vs. Penn State Nittany Lions | Iowa Hawkeyes vs. Penn State Nittany Lions | Kinnick Stadium | Kinnick Stadium
Iowa City, IA | 10/20/2012 3:30 AM | Oct 20, 2012 TBA | View Tickets |
| Northwestern Wildcats vs. Iowa Hawkeyes | Northwestern Wildcats vs. Iowa Hawkeyes | Ryan Field | Ryan Field
Evanston, IL | 10/27/2012 3:30 AM | Oct 27, 2012 TBA | View Tickets |
| Indiana Hoosiers vs. Iowa Hawkeyes | Indiana Hoosiers vs. Iowa Hawkeyes | Memorial Stadium - IN | Memorial Stadium - IN
Bloomington, IN | 11/03/2012 3:30 AM | Nov 03, 2012 TBA | View Tickets |
| Iowa Hawkeyes vs. Purdue Boilermakers | Iowa Hawkeyes vs. Purdue Boilermakers | Kinnick Stadium | Kinnick Stadium
Iowa City, IA | 11/10/2012 3:30 AM | Nov 10, 2012 TBA | View Tickets |
| Michigan Wolverines vs. Iowa Hawkeyes | Michigan Wolverines vs. Iowa Hawkeyes | Michigan Stadium | Michigan Stadium
Ann Arbor, MI | 11/17/2012 3:30 AM | Nov 17, 2012 TBA | View Tickets |
| Iowa Hawkeyes vs. Nebraska Cornhuskers | Iowa Hawkeyes vs. Nebraska Cornhuskers | Kinnick Stadium | Kinnick Stadium
Iowa City, IA | 11/23/2012 3:30 AM | Nov 23, 2012 TBA | View Tickets |
| Penn State Nittany Lions vs. Wisconsin Badgers | Penn State Nittany Lions vs. Wisconsin Badgers | Beaver Stadium | Beaver Stadium
University Park, PA | 11/24/2012 3:30 AM | Nov 24, 2012 TBA | View Tickets |